E L Edghill Selected Research

pancreatic and duodenal homeobox 1 protein

5/2013	Biallelic PDX1 (insulin promoter factor 1) mutations causing neonatal diabetes without exocrine pancreatic insufficiency.
6/2011	Sequencing PDX1 (insulin promoter factor 1) in 1788 UK individuals found 5% had a low frequency coding variant, but these variants are not associated with Type 2 diabetes.

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E L Edghill Research Topics

Disease

4	Type 2 Diabetes Mellitus (MODY) 01/2012 - 01/2006
2	Cysts 01/2013 - 01/2006
1	Exocrine Pancreatic Insufficiency 05/2013
1	Mason-Type Diabetes 01/2013
1	Insulinoma 10/2009
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2009
1	Fetal Growth Retardation (Intrauterine Growth Retardation) 12/2006
1	Birth Weight (Birth Weights) 12/2006
1	Atrophy 01/2006
1	Gout 01/2006

Drug/Important Bio-Agent (IBA)

2	pancreatic and duodenal homeobox 1 proteinIBA 05/2013 - 06/2011
2	NFI Transcription FactorsIBA 11/2007 - 12/2006
2	Hepatocyte Nuclear Factor 1-betaIBA 12/2006 - 01/2006
1	Hepatocyte Nuclear FactorsIBA 01/2013
1	AntibodiesIBA 10/2009
1	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 10/2009
1	AutoantibodiesIBA 10/2009
1	Hepatocyte Nuclear Factor 1-alpha (Hepatocyte Nuclear Factor 1 alpha)IBA 11/2007
1	GlucokinaseIBA 11/2007
1	Transcription Factors (Transcription Factor)IBA 11/2007

Therapy/Procedure

1	Ligation 01/2013
1	Therapeutics 01/2012